dog cbd

A dog being given CBD hemp oil. (Credit: 24K-Production on Shutterstock)

Cranky first, calm later: Dogs given CBD had high aggression scores initially, but mellowed out over time.

In A Nutshell

  • Dogs given CBD for at least 2 years showed declining aggressive behaviors over time, while dogs not on CBD maintained steadier aggression levels throughout the study period
  • CBD-using dogs started with higher aggression scores, suggesting owners turned to the supplement specifically to manage behavioral problems in their pets
  • The study tracked 47,355 dogs nationwide and found CBD use was most common in dogs with dementia (18.2%), arthritis (12.5%), and epilepsy (10.6%)
  • Researchers caution the behavioral improvements could stem from training or other interventions owners used alongside CBD, not the supplement itself

Dogs receiving CBD supplements showed a notable decline in owner-reported aggressive behaviors over time compared to dogs not given the compound, according to an observational study. The research initiative, put together by the Dog Aging Project, tracked nearly 50,000 companion dogs across the United States.

The finding suggests CBD could play a role in managing canine aggression, though researchers caution that owners may have simultaneously used training or other interventions that contributed to the behavioral changes.

Dogs consistently given CBD for at least two years initially displayed higher-than-average aggression levels compared to dogs never given the supplement. Over time, however, their aggressive behaviors declined at a faster rate. By the end of the study period, these dogs showed below-average aggression compared to their non-CBD counterparts.

“The decline in the intensity of aggressive behaviors suggests the potential use of CBD in dog training,” the researchers wrote in their paper published in Frontiers in Veterinary Science.

CBD Dogs Started More Aggressive But Improved Faster

The study analyzed survey data from 47,355 dogs enrolled in the Dog Aging Project between December 2019 and December 2023. Owners completed annual surveys about their dogs’ behaviors using a modified version of the Canine Behavioral Assessment & Research Questionnaire, which researchers used to create behavior scores based on reactions to various situations including interactions with strangers, other animals, and unfamiliar circumstances.

Among the behaviors tracked, aggression stood out as showing the most significant difference between CBD and non-CBD groups over time. Dogs receiving CBD also showed declining intensity in reactions to unfamiliar circumstances and reactions to other animals, two separate behavioral measures that researchers tracked alongside aggression.

The fact that CBD-using dogs started with higher aggression levels hints that owners may have turned to the supplement specifically to address behavioral issues. Around 5.5% of all dogs in the study received CBD at some frequency, with owners most commonly administering it as a daily supplement.

The behavioral improvements over time raise questions about what exactly drove the changes. CBD might be directly affecting the dogs’ temperament, or the improvements could stem from owners taking multiple steps to address aggression, such as working with trainers or veterinarians.

Previous controlled studies have shown CBD can reduce stress-related behaviors in dogs during separation and car travel. One study found shelter dogs given CBD displayed less aggression toward humans, aligning with the current findings.

Dogs are also being given CBD to address numerous health issues ranging from dementia to diarrhea.
Dogs are also being given CBD to address numerous health issues ranging from dementia to diarrhea. (Credit: New Africa on Shutterstock)

Health Problems Remain Primary Reason for CBD Use

Beyond behavior, owners primarily gave CBD to dogs with specific health conditions. Dogs with dementia showed the highest rate of CBD use at 18.2%, followed by those with osteoarthritis at 12.5% and epilepsy at 10.6%.

The study found seven health conditions significantly associated with CBD use: dementia, osteoarthritis, epilepsy, hip dysplasia, cancer, chronic diarrhea, and a group of ongoing digestive problems such as repeated vomiting or constipation. Researchers noted that some of these associations reflect established therapeutic uses, like CBD for epilepsy, while others may simply reflect owner perceptions about CBD’s health benefits.

Interestingly, dogs with gastrointestinal problems and chronic diarrhea were more likely to receive CBD, even though these symptoms can be side effects of CBD supplementation in dogs.

Age and Location Patterns in CBD Use

Dogs receiving CBD frequently (daily or as non-prescription medication) averaged 10.2 years old, while those with infrequent use averaged 8.1 years, compared to 7.6 years for dogs not given the supplement. Male dogs showed slightly higher CBD use rates than females, though researchers couldn’t explain the gender gap.

Geographic patterns revealed how human attitudes toward cannabis influence pet care choices. Dogs in states with legal medical cannabis programs had higher CBD usage rates compared to states without medical cannabis programs. On average, 5.8% of dogs in medical cannabis states received CBD versus 4.7% in states without such programs.

CBD use varied by location, ranging from 1.6% in Iowa to 9.7% in Hawaii. Among breeds, Leonbergers showed the highest CBD use rate at 10.3% for purebreds with more than 50 dogs surveyed.

What This Means for Dog Owners

The research relied entirely on owner-reported data, which introduces potential bias and limits the ability to draw causal conclusions. Owners may have misreported or failed to report CBD use, and the study lacked information about CBD product composition, dosages, and specific formulations.

Researchers emphasized that the behavioral improvements could result from training, other medications, or lifestyle changes owners implemented alongside CBD. Future randomized clinical trials with measurable data like cortisol levels and activity tracking would help establish whether CBD directly causes behavioral changes and identify proper dosing.

The study represents the largest assessment of CBD use in companion animals to date and provides a foundation for understanding how the human-animal bond influences health decisions for both species.


Disclaimer: This article is for informational purposes only and does not constitute veterinary medical advice. Always consult with a licensed veterinarian before starting, stopping, or changing any supplements or medications for your pet. The observational study discussed cannot prove cause and effect between CBD use and behavioral changes in dogs.


Paper Summary

Limitations

The study relied on owner-reported survey data rather than clinical measurements, making it subject to owner bias and perceptions. Dogs could be misclassified into usage categories if owners failed to report or misreported CBD administration. The observational nature prevents drawing causal conclusions about CBD’s effects. The study lacked data on CBD product composition, cannabinoid dosages, formulations, administration routes, and product sources. Dog Aging Project participants tend to be older and wealthier than the U.S. general population, with a median age range of 55 to 64 and income of $100,000 to $119,999 compared to national medians of 39 years and $80,610, limiting generalizability to diverse socioeconomic populations.

Funding and Disclosures

The Dog Aging Project received support from the National Institutes of Health (grant no. U19-AG057377) and private donations. Daniel Promislow received additional support from the United States Department of Agriculture cooperative agreement USDA/ARS 58-8050-9-004. The authors declared no commercial or financial conflicts of interest. One author disclosed being an editorial board member of Frontiers at the time of submission, which had no impact on peer review.

Publication Information

The study was authored by Kendra D. Conrow and Richard S. Haney (School of Mathematical and Natural Sciences, Arizona State University), Michael H. Malek-Ahmadi (Banner Alzheimer’s Institute), Julia D. Albright (College of Veterinary Medicine, University of Tennessee), Barbara L. F. Kaplan (College of Veterinary Medicine, Mississippi State University), Noah Snyder-Mackler (School of Life Sciences, Arizona State University), Kathleen F. Kerr (School of Public Health, University of Washington), Yi Su (Banner Alzheimer’s Institute), Daniel E. L. Promislow (Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University), Emily E. Bray (College of Veterinary Medicine, University of Arizona), and Maxwell C. K. Leung (School of Mathematical and Natural Sciences, Arizona State University), along with the Dog Aging Project Consortium. Published in Frontiers in Veterinary Science, Volume 12, November 28, 2025. DOI: 10.3389/fvets.2025.1666663.

About StudyFinds Analysis

Called "brilliant," "fantastic," and "spot on" by scientists and researchers, our acclaimed StudyFinds Analysis articles are created using an exclusive AI-based model with complete human oversight by the StudyFinds Editorial Team. For these articles, we use an unparalleled LLM process across multiple systems to analyze entire journal papers, extract data, and create accurate, accessible content. Our writing and editing team proofreads and polishes each and every article before publishing. With recent studies showing that artificial intelligence can interpret scientific research as well as (or even better) than field experts and specialists, StudyFinds was among the earliest to adopt and test this technology before approving its widespread use on our site. We stand by our practice and continuously update our processes to ensure the very highest level of accuracy. Read our AI Policy (link below) for more information.

Our Editorial Process

StudyFinds publishes digestible, agenda-free, transparent research summaries that are intended to inform the reader as well as stir civil, educated debate. We do not agree nor disagree with any of the studies we post, rather, we encourage our readers to debate the veracity of the findings themselves. All articles published on StudyFinds are vetted by our editors prior to publication and include links back to the source or corresponding journal article, if possible.

Our Editorial Team

Steve Fink

Editor-in-Chief

John Anderer

Associate Editor

Leave a Comment