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In a Nutshell
- Across nearly 500,000 births, epidural pain relief in labor showed no link to the serious newborn and childhood problems studied, from neurological injury to infection and death.
- Babies faced no added risk even in higher-risk situations, including preterm birth and emergency cesarean delivery.
- Only about 23% of women in Scotland chose an epidural, well below the 70%-plus rate common in the United States; the authors say the findings could ease a common worry and support clearer conversations about pain relief.
For decades, one question has followed pregnant women into the delivery room: will an epidural hurt my baby? That worry has led many to endure severe labor pain rather than accept the most effective relief on offer. A new national study out of Scotland, among the largest of its kind, found no meaningful link between epidural pain relief during labor and the serious newborn and childhood health problems it examined, including neurological injury in newborns.
Published in the medical journal The BMJ, the research tracked nearly half a million births at every NHS hospital in Scotland over 13 years. Researchers asked whether mothers who received an epidural were more likely to have babies who suffered serious neurological problems, severe newborn illness, blood infections, very low Apgar scores, death within 28 days, or cerebral palsy in childhood. Across the outcomes they measured, epidurals carried no added risk.
That reassurance held even for the babies usually considered most fragile: those born prematurely, those born to mothers with high-risk pregnancies, and those delivered by emergency cesarean.
A Long-Unanswered Question About Epidural Safety
Epidurals are widely regarded as the most effective pain relief available in labor, and earlier research suggests they may also protect mothers from severe complications. Yet the conversation around them has often been lopsided. Maternal risks tend to get a thorough airing, while possible effects on the baby are raised less consistently, or skipped altogether because the evidence was thin.
Comfort is not the whole story, either. Work by the same Scottish team has linked epidurals to fewer severe complications for mothers, particularly in high-risk pregnancies. Still, the gap in evidence about babies mattered. Women often name worry about their baby as a reason for turning down an epidural, and the concern was not baseless, since epidurals can trigger side effects in mothers, such as fever and blood pressure changes, that could in theory reach the baby. What was missing was large-scale evidence on serious, long-term outcomes for children.
How the Epidural Study Tracked Nearly 500,000 Births
Researchers reviewed records from 495,695 women who gave birth in Scotland between 2007 and 2019, drawing on six linked national health databases that captured everything from delivery details to childhood diagnoses. About 23% of them, or 114,897 women, received an epidural during labor.
Their main focus was serious neurological trouble in newborns during the first 28 days, a category that included brain injury from oxygen loss at birth, seizures, and bleeding in the brain.
To keep the comparison fair, the team adjusted for factors that could tilt the results, among them the mother’s age, weight, smoking history, socioeconomic background, whether labor was induced, and whether she had diabetes or preeclampsia. Women who delivered at home or in midwife-led units without epidural access were counted separately. Researchers also ran the numbers several more ways, including an analysis limited to straightforward vaginal births, and the picture did not change.
What the Data Showed About Newborn Outcomes
Serious neurological problems were rare throughout, showing up in 434 babies, roughly 0.9 per 1,000 births. After accounting for other factors, that rate was no different between babies whose mothers had an epidural and those whose mothers did not. Severe newborn illness, blood infection, newborn death, and childhood cerebral palsy told the same story.
One finding pointed in the other direction. Among preterm babies, those whose mothers had an epidural were less likely to score poorly on the five-minute Apgar check, though the authors urged caution and called for more study before reading too much into it.
Epidurals can also raise a mother’s temperature, and fever during labor has been tied to newborn problems. This study could not measure temperature directly, but its results line up with earlier work that found no clear link between epidural-related fever and serious harm to babies.
Why Many Women Still Decline Epidurals
Even though epidurals are free through the NHS, only about 23% of women in this group chose one, in line with the rest of the UK at the time. In the United States, the figure can top 70%. According to the authors, lower uptake in the UK may stem from misinformation, cultural attitudes, distrust of providers, and fear of harming the baby, though they present these as possible explanations rather than proven causes. They also note that women from lower-income areas and ethnic minority communities are less likely to opt for an epidural, even though they more often have high-risk pregnancies.
For the authors, the message is direct: a woman weighing an epidural should not have to trade her own pain relief against her baby’s safety. They conclude that, for the serious outcomes examined, that trade-off does not hold up. In their words, the results show that “epidural analgesia use in labour is safe for babies.”
Disclaimer: This article summarizes the findings of a single observational study for general information and is not medical advice. An observational study can show that two things are connected but cannot prove that one causes the other; the results reflect only the specific outcomes the researchers measured, not every possible effect. Decisions about pain relief during labor depend on individual circumstances and should be made in consultation with a qualified healthcare provider.
Paper Notes
Limitations
This was an observational study, meaning the researchers analyzed existing records rather than randomly assigning women to receive an epidural or not. Because of that design, unmeasured differences between the two groups of women could still explain part of the results. Women who choose an epidural differ from those who don’t in several ways, including how often their labor is induced and how complicated their medical histories are, and not all of those differences could be fully accounted for.
Several practical details were missing from the databases: the total duration of labor, the specific reason for choosing an epidural, how long it remained in place, and the level of distress the baby showed before delivery. Maternal temperature and blood pressure were not recorded either, so the researchers could not directly test whether epidural-related fever affected newborns. Diagnoses came from administrative billing codes rather than full clinical charts, which can miss or misclassify some cases. Data on ethnicity were unavailable for 37.5% of participants, and because Scotland’s population is mostly white, the results may not translate neatly to more diverse populations, though the authors note that their numbers matched those of a more diverse U.S. study.
Because the most serious outcomes were rare, the study had limited ability to detect very small increases in risk. Even so, the authors say their data effectively rule out any increase in the main risk of more than 12%, a threshold they consider meaningful in the clinic.
Funding and Disclosures
This work was supported by an NHS Greater Glasgow and Clyde senior researcher fellowship, a research project grant from Wellbeing of Women–Chief Scientist Office, and a Chief Scientist Office (Scotland) PhD fellowship. Additional support came from the UK Medical Research Council and the British Heart Foundation. None of the funders had any role in the design, data analysis, or interpretation of results. Several authors disclosed consulting fees, speakers’ fees, or advisory board participation with organizations unrelated to this study. Full disclosures are available through the ICMJE disclosure form referenced in the paper.
Publication Details
Paper title: Epidural analgesia in labour and neonatal and childhood outcomes: national population-based cohort study
Authors: Rachel J Kearns, Aizhan Kyzayeva, Sarjit Singh, Deborah A Lawlor, Martin Shaw, Scott Nelson
Journal: The BMJ
Citation: BMJ 2026;394:e343320
Published: July 15, 2026







