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In A Nutshell
- Nearly 1 in 3 American teenagers has prediabetes or type 2 diabetes, with the vast majority of cases being prediabetes, which is reversible if caught early.
- Boys are far more likely to be affected than girls, making up 62 percent of cases in the study.
- Waist-to-height ratio, a simple tape-measure calculation, was a far stronger predictor of diabetes risk than BMI, which lost significance once other factors were considered.
- Diet and exercise habits did not independently predict risk once body fat distribution was accounted for, suggesting that where fat is stored matters more than lifestyle factors alone.
Walk into any middle school classroom in America and look around. Statistically, about one in three of those kids already has prediabetes or type 2 diabetes (T2DM), conditions most people associate with overweight adults in their 40s and 50s. That is the central finding of a new study, and it is as alarming as it sounds.
Researchers analyzed federal health data on nearly 2,000 adolescents ages 10 to 19 and found that 30.8 percent had blood sugar levels in the prediabetes or type 2 diabetes range. To be clear, the overwhelming majority of those cases were prediabetes. Only five participants out of 1,998 had a confirmed type 2 diabetes diagnosis. But prediabetes in a teenager is far from trivial. Left unaddressed, it can become the real thing. That figure comes from the National Health and Nutrition Examination Survey (NHANES), a nationally representative program run by the Centers for Disease Control and Prevention, covering 2021 through 2023. It reflects a trend building for more than two decades, driven by rising obesity rates, sedentary lifestyles, and diets heavy in processed food.
What makes the numbers especially concerning is what youth-onset diabetes actually means for a child’s future. Previous research shows that type 2 diabetes diagnosed in teenagers often progresses faster than when it develops later in life, with complications including kidney damage, nerve problems, and vision loss arriving sooner. Early prediabetes, where blood sugar is elevated but not yet in the diabetic range, is reversible. Once type 2 diabetes takes hold, it is not.
Teen Prediabetes Rates Are Disproportionately High Among Boys
The study included 1,998 adolescents, nearly evenly split between males and females, with an average age of about 14. Prediabetes was defined using two standard clinical measures: a hemoglobin A1c reading, a blood test reflecting average blood sugar over the previous two to three months, of 5.7 percent or higher, or a fasting blood glucose of at least 100 mg/dL. These are the same thresholds doctors use for adults. Only five participants had a confirmed type 2 diabetes diagnosis, so the researchers grouped prediabetes and T2DM together to produce reliable statistical estimates.
Among adolescents with elevated blood sugar, boys made up 62 percent of cases compared to 38 percent for girls, a gap that held even after the researchers accounted for other factors. The study’s author points to potential biological explanations, including the tendency for males to accumulate more visceral fat, the kind that settles around internal organs rather than just under the skin, and the possible role of male sex hormones in reducing the body’s sensitivity to insulin. The pattern tracks with other U.S. and international research, as well as a large global review of adolescent prediabetes data.
Younger adolescents also showed somewhat higher risk than older teens, another counterintuitive wrinkle for clinicians who might assume risk only grows with age.

Why BMI Keeps Missing High-Risk Teens With Prediabetes
One of the most consequential findings involves what the researchers measured and what that measurement actually predicted. Body mass index, or BMI, has long been the default screening tool in pediatric care. It is simple to calculate from height and weight, and familiar to most parents. But when the full statistical model was run, accounting for waist-to-height ratio and other factors, BMI-based overweight and obesity was no longer an independent predictor of prediabetes or T2DM. It mattered in isolation, but not once the bigger picture was in view.
The measure that dominated was the waist-to-height ratio, a person’s waist circumference divided by their height. A ratio at or above 0.5 signals central obesity, meaning excess fat concentrated in the midsection. Of the adolescents in the study, 40.8 percent met that threshold. Those with an elevated waist-to-height ratio had more than 146 times the odds of prediabetes or T2DM compared to those with a healthy ratio. That number demands context: the statistical range behind it runs from roughly 5-fold to nearly 4,000-fold, an unusually wide spread that reflects how few confirmed T2DM cases were in the sample. The figure is not precise enough to take literally, but the core signal is real and consistent with a growing body of research on central fat and metabolic risk in young people.
A 2013 study found that waist-to-height ratio explained 64 percent of the variation in body fat percentage among American children and adolescents, versus just 32 percent for BMI, with predictive accuracy climbing to 80 percent after adjusting for age and sex. A teenager who looks only mildly overweight on a standard growth chart might already be carrying enough abdominal fat to seriously raise metabolic risk, and a routine BMI check would not catch it.
What Diet and Exercise Data Revealed About Teen Diabetes Risk
In the initial analysis, factors like sugar intake and overweight status were linked to elevated blood sugar. But once body composition was fully accounted for, lifestyle variables including sedentary time, physical activity, daily calorie intake, and sugar consumption stopped being significant independent predictors on their own.
The researchers interpret this as evidence that where fat is stored in the body drives much of the effect that lifestyle has on blood sugar. Inactivity and poor diet likely raise diabetes risk by contributing to central fat accumulation. Once that accumulation is measured directly, the individual habits recede into the background statistically.
That does not let unhealthy behavior off the hook. Nearly 89 percent of the adolescents in the sample spent two or more hours per day in front of screens, and only about 21 percent met physical activity guidelines. Those habits almost certainly contribute to the fat accumulation that is, in turn, driving the blood sugar numbers upward. The chain of cause and effect is just more direct than standard public health messaging tends to suggest.

Rethinking How Doctors Screen for Teen Prediabetes
With nearly 1 in 3 American adolescents already showing signs of metabolic trouble, the window for meaningful prevention is narrow. The study, published in PLOS Global Public Health, points to a concrete and inexpensive step pediatricians can take right now: add a tape measure to the standard checkup and calculate waist-to-height ratio alongside BMI. The calculation takes about 30 seconds and captures something BMI cannot, namely where excess fat sits in the body and what that location signals about a teenager’s long-term health trajectory. Given the disproportionate burden among younger male adolescents, boys in early to mid adolescence may warrant the closest attention.
For a condition now affecting roughly 1 in 3 American teens, a tape measure and a simple ratio seem like a reasonable place to start.
Disclaimer: This article is based on a single observational study and is intended for informational purposes only. The findings reflect associations, not proven causes. Parents and caregivers with concerns about a child’s blood sugar or metabolic health should consult a qualified healthcare provider.
Paper Notes
Study Limitations
This study used a cross-sectional design, capturing each participant at a single point in time rather than following them over months or years. That approach cannot establish whether the risk factors identified caused prediabetes or T2DM, only that they were associated with it. Blood sugar was measured once, and adolescents’ levels can vary, meaning some participants may have been misclassified. Dietary intake and physical activity were self-reported and may not accurately reflect real-world behavior. The margin of uncertainty for the waist-to-height ratio finding was very wide, reflecting limited precision due to the small number of confirmed T2DM cases, and should be interpreted carefully pending replication in larger studies.
Funding and Disclosures
The author received no specific funding for this work. No competing interests were declared. Data used in the analysis are publicly available from the CDC’s NHANES program and required no additional institutional review board approval.
Publication Details
Author: Eric Peprah Osei, College of Nursing, University of Illinois Chicago; Ghana Health Service, Dormaa West District Hospital, Bono Region, Ghana. | Journal: PLOS Global Public Health | Title: Prevalence and predictors of prediabetes/type 2 diabetes mellitus among adolescents in the United States: NHANES (2021–2023) | Published: February 25, 2026 | DOI: https://doi.org/10.1371/journal.pgph.0005596 | Citation: Peprah Osei E (2026) Prevalence and predictors of prediabetes/type 2 diabetes mellitus among adolescents in the United States: NHANES (2021–2023). PLOS Glob Public Health 6(2): e0005596.








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