seaweed cookies

Even with an addition of just 1%, the seaweed significantly increased the phenolic compound content and antioxidant activity of the cookies (Credit: Bruna Lago Tagliapietra)

Seaweed Flour Could Give Gluten-Free Cookies a Nutritional Upgrade With Just a 1% Swap, Study Finds

In A Nutshell

  • Brazilian researchers replaced just 1% of rice flour in gluten-free biscuits with dried seaweed flour and produced a softer, more mineral-rich cookie with higher antioxidant activity.
  • The seaweed-enriched biscuits required significantly less force to break and retained more moisture, without affecting shape, size, or blood sugar response.
  • Antioxidant activity in the seaweed biscuits stayed consistently higher than the control cookies throughout a simulated digestion process, from stomach to intestine.
  • Results came from a lab study using simulated digestion, not human trials, and no taste panel was conducted, so consumer acceptance and real-world nutrition benefits remain to be confirmed.

For people who can’t eat gluten, cookies and crackers often come with a trade-off. Gluten-free versions tend to taste fine, but most are built on a base of refined rice or potato starch that leaves them short on fiber, protein, and antioxidant activity. Researchers may have found an unlikely fix washing up along the Brazilian coast. A brown seaweed that has been largely overlooked as a food ingredient could be exactly what gluten-free baked goods have been missing.

A new study published in Food Research International found that grinding this seaweed, called Sargassum filipendula, into a fine flour and replacing just 1% of the rice flour in a gluten-free biscuit recipe produced a softer cookie with more minerals, higher antioxidant activity, and signs of improved protein digestibility in a lab digestion model. That mineral boost would still need safety checks before any product reached shelves, since seaweeds can concentrate minerals such as iodine. The seaweed flour also turned the biscuits darker and more yellow-brown, thanks to natural pigments in the algae.

For people with celiac disease, a condition where eating gluten triggers a damaging immune response in the gut, or others who must avoid gluten entirely, gluten-free products are a dietary necessity. This research points to marine algae, particularly an underused species abundant off the coast of Brazil, as one practical avenue for closing the nutritional gap.

Why This Seaweed Stands Out as a Gluten-Free Ingredient

Before incorporating the seaweed into any recipe, researchers first analyzed the dried flour on its own. It contained high protein and an especially high mineral concentration, more than 26 grams of ash per 100 grams, a standard measure of total mineral load. It also showed strong antioxidant activity even before being baked into anything.

When the seaweed flour was run through a simulated digestion on its own, its antioxidant activity kept climbing all the way through the four-hour intestinal digestion phase. The finished biscuits also stayed consistently higher in antioxidant activity than the control cookies at every stage of digestion.

brown seaweed
A) Sargassum filipendula in its natural habitat, affixed to the rocky coast; B) Collection of seaweed at Praia das Cigarras, São Sebastião, SP, Brazil on September 12th, 2024. (Credit: Tagliapietra, B.Tagliapietra, B. L., Clerici, M. T. P. S., & Martínez-Villaluenga, C. (2026). Sargassum filipendula flour improves composition, digestibility, and antioxidant activity of gluten-free biscuits. Food Research International, 234, Article 118906. https://doi.org/10.1016/j.foodres.2026.118906)

What Researchers Did to Test Seaweed Flour in Gluten-Free Biscuits

Fresh Sargassum filipendula was collected from the Brazilian coast, thoroughly rinsed to remove surface organisms, then deep-frozen and freeze-dried for 48 hours until it reached a moisture level below 6%. It was ground into a flour with particles no larger than half a millimeter.

Researchers then baked two batches of gluten-free biscuits: a control batch made with 100% rice flour, and a test batch where 1% of the rice flour was swapped for seaweed flour. All other ingredients, potato starch, sunflower oil, eggs, salt, and water, stayed the same. Both versions went through tests measuring color, hardness, mineral content, and how the biscuits’ carbohydrates behaved when heated. Lab simulations of the full digestive process, from mouth to intestine, tracked how well proteins broke down and how much antioxidant activity was released at each stage. An estimated glycemic index was calculated for both versions.

Softer, Richer, Darker: What the Seaweed Biscuits Looked Like

When comparing the two versions, the seaweed-enriched cookies stood out in several ways. They had measurably higher mineral content and higher moisture, linked to certain seaweed compounds that hold onto water during baking.

On texture, the seaweed biscuits required significantly less force to break, 18.47 Newtons compared to 27.61 Newtons for the control. Dietary fiber in the seaweed flour holds water within the biscuit structure and reduces how tightly packed the starchy network becomes, which researchers said likely produced the softer texture.

Color was another clear point of difference. A color difference score of 55.42 was recorded between the two batches, well above the threshold of 3 that researchers consider visible to the naked eye. That shift came from natural pigments in the algae.

On blood sugar response, both versions were identical, each registering an estimated glycemic index of approximately 62. Seaweed fiber has been shown in other research to slow starch digestion. Researchers suggested the 1% substitution level may have been too small to produce a measurable difference in glycemic response, but the result also means the addition did not make things worse.

What This Means for the Future of Gluten-Free Baking

Researchers were careful to note that the study used simulated digestion rather than human clinical trials, and no tasting panel was conducted, so how consumers would respond to the darker, more yellow-brown biscuit remains an open question.

There’s also the matter of food regulation. In Brazil, seaweeds can be used as food ingredients provided they meet safety and quality standards, including close attention to mineral levels like iodine, which can concentrate at high levels in certain algae. Regulatory pathways differ across markets and would need to be navigated before any product reached store shelves.

Swapping out just one percent of rice flour for a freeze-dried, ground seaweed abundant along the Brazilian coast was enough to produce a biscuit that was softer, richer in minerals, and more antioxidant-active throughout simulated digestion. For a food category long criticized for falling short on nourishment, that’s a meaningful result from a very small change.


Disclaimer: This article is based on a published peer-reviewed study. It is intended for informational purposes only and does not constitute medical or nutritional advice. The findings reflect laboratory research and have not been confirmed in human clinical trials.


Paper Notes

Limitations

The study was conducted entirely in a laboratory setting using simulated, not human, digestion models, which may not perfectly reflect how a real digestive system processes food. The experiment was carried out in a single experimental run, with three independent baking batches per formulation; the simulated digestion was performed in duplicate. Only one substitution level (1%) was tested, and the study did not include a sensory evaluation with human panelists, so consumer acceptance and palatability responses are not yet known. Protein digestibility values from other algae species cannot be directly compared to the results here due to structural differences between species. The glycemic index was estimated using a laboratory method rather than a clinical study with human participants. The researchers also note that seasonal variability in seaweed composition was not evaluated and should be considered in future investigations.

Funding and Disclosures

Funding was provided by the Spanish Ministry of Science, Innovation and Universities / State Research Agency (MICIU/AEI) and the European Regional Development Fund (FEDER, EU) under grant PID2022-138978OB-I00. Additional support came from Brazil’s National Council for Scientific and Technological Development (CNPq), which provided a scholarship to co-author M. T. P. Clerici, and from the São Paulo Research Foundation (FAPESP, process number 2023/12726-8), which funded a postdoctoral fellowship for lead author B. L. Tagliapietra. Co-author C. Martínez-Villaluenga is a member of the InnoProt network funded by CYTED (ref. 124RT0164). The authors declare no competing financial interests.

Publication Details

Authors: Bruna Lago Tagliapietra (Universidade Estadual de Campinas, School of Food Engineering, Campinas, São Paulo, Brazil; Federal University of Santa Maria, Palmeira das Missões, RS, Brazil); Maria Teresa Pedrosa Silva Clerici (Universidade Estadual de Campinas, Campinas, São Paulo, Brazil); Cristina Martínez-Villaluenga (Institute of Food Science, Technology, and Nutrition, ICTAN-CSIC, Madrid, Spain) | Journal: Food Research International, Volume 234 (2026), Article 118906 | Paper Title: “Sargassum filipendula flour improves composition, digestibility, and antioxidant activity of gluten-free biscuits” | DOI: https://doi.org/10.1016/j.foodres.2026.118906 | Published online: March 26, 2026

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