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Overworked Men Face Ten Times the Odds of Erectile Dysfunction
In A Nutshell
- Men with the heaviest job-related stress had about ten times the odds of erectile dysfunction compared with the least-stressed men in a study of 826 workers.
- More than half of the most stressed men reported erectile dysfunction, versus just 8% of the least stressed.
- Morning cortisol rose about 74% and testosterone dropped by more than a third in the most stressed men, changes that statistically explained close to 40% of the stress-ED link.
- Researchers estimate a six-to-ten-week gap between rising stress hormones and the onset of erectile trouble, a window that could allow early intervention.
A demanding boss, back-to-back overtime, and a career that feels stuck might drain more than a young man’s energy. New research published in the International Journal of Clinical Practice, tracking 826 working men, suggests that pressure on the job is linked to something far more personal: sexual function. Men carrying the heaviest load of job-related stress had about ten times the odds of erectile dysfunction compared with men in the lowest-stress group, a gap large enough to make workplace stress worth taking seriously as a possible contributor to sexual-health problems.
To measure that pressure, scientists built a stress-tracking tool combining five factors: weekly work hours, decision-making freedom, supervisor support, coworker relationships, and promotion pressure. Men who scored highest on this combined scale had far lower scores on a standard erectile-function questionnaire than men who scored lowest. Blood tests told a matching story: cortisol, the body’s main stress hormone, climbed higher in the most stressed men, while testosterone dropped lower.
That association did not appear to build gradually. Erectile-function scores stayed relatively steady at lower stress levels, then dropped more sharply once stress crossed a certain threshold, more like flipping a switch than sliding down a slope. Researchers also traced a possible hormonal sequence behind that pattern, detailed further below.
Five Job Factors Combined Into One Stress Score Outpredicted Older Tools
Researchers recruited 826 full-time working men between ages 22 and 40 from a hospital urology department in China, gathering data from March 2022 to August 2024. Participants averaged just over 31 years old. To rule out other causes of erection problems, the team excluded men with diabetes, heart disease, spinal injuries, hormone disorders, medications known to affect sexual function, or night and rotating shift work.
Instead of relying on a single stress survey, researchers built a combined score called the Workplace Psychological Stress Accumulation Index, shaped by a panel of fifteen experts in medicine, psychology, and male sexual health. The final score folded work hours, decision-making freedom, supervisor support, coworker relationships, and promotion pressure into one number, and it predicted erectile dysfunction more accurately than two existing, widely used stress scales.
Erectile function was measured with a standard five-question survey used worldwide in men’s health research, with scores ranging from 5, indicating severe dysfunction, to 25, indicating normal function. Blood drawn in the morning and at night measured cortisol, testosterone, and related hormones, letting researchers track how levels rose and fell across the day.
More Than Half of the Most Stressed Workers Had Erectile Dysfunction
Participants were split into four groups by stress score, from lowest to highest. Only 8.21% of men in the lowest-stress group reported erectile dysfunction, compared with 54.37% in the highest-stress group. Average erectile-function scores fell steadily too, from a near-normal 22.86 to 15.28, within dysfunction range.
After adjusting for age, weight, smoking, and drinking, men in the highest-stress group had 10.26 times the odds of erectile dysfunction versus the lowest-stress group. Long working hours emerged as the single biggest factor: each additional ten hours of work per week was tied to a measurable drop in erectile-function scores. Supervisor support acted as a buffer, and that protective effect was strongest among men working the longest hours.
Cortisol Rose 74 Percent in the Most Stressed Men, Testosterone Fell
Blood tests backed up the questionnaire results. Morning cortisol rose sharply, up by about 74% between the lowest and highest stress groups, while testosterone dropped by more than a third. Cortisol’s normal daily rhythm, which is supposed to peak in the morning and fall by night, also flattened out in the most stressed men, a pattern researchers say points to a stress system running in overdrive around the clock.
Statistical mediation analysis found that hormone changes accounted for close to 40% of the connection between workplace stress and erectile trouble, with cortisol contributing the largest share. The rest likely runs through pathways the hormone tests could not capture.
Timing may be the most useful part of the study for prevention. Cortisol changes appeared roughly two to four weeks before testosterone began dropping, and testosterone decline preceded changes in erectile function by another four to six weeks. The authors describe this as a possible six-to-ten-week intervention window based on statistical modeling, not a proven timeline for any individual man.
Combined Model Sorted Men Into Risk Groups With Up to 68 Percent ED Rates
Researchers combined the stress index with two hormone measurements into a single model, which identified erectile dysfunction risk more accurately than any single measurement alone. Sorted by risk, men fell into low, medium, and high-risk groups with erectile dysfunction rates of 9.2%, 31.6%, and 68.4% respectively.
Erectile dysfunction has long been treated as a plumbing problem or an aging problem, managed with medication once it appears. This research suggests a different story, one where trouble at the office can shape what happens in the bedroom weeks later. The study cannot prove that job stress causes erectile dysfunction, and it drew from a single hospital department in China with several medical and occupational groups excluded. Still, the association is strong enough that catching it early may matter as much as treating it after the fact.
Disclaimer: This article summarizes findings from a single peer-reviewed study and is intended for general informational purposes. It is not a substitute for professional medical advice. Anyone experiencing symptoms of erectile dysfunction or concerned about workplace stress should speak with a qualified healthcare provider.
Paper Notes
Limitations
The study relied on men recruited from a single hospital urology department in China, so the results may not reflect men in other countries, industries, or cultural work environments. The design captured data at set points in time and estimated hormone and symptom timing through statistical modeling rather than following individual men continuously over months, so the six-to-ten-week window is a modeled estimate, not a directly observed sequence for each participant. The paper does not report on whether findings would hold for men outside the 22 to 40 age range, for shift workers who were excluded, or for men in remote or freelance work arrangements. As an observational study, it establishes association, not proof of causation.
Funding and Disclosures
The study was supported by the Project of Jiangsu Provincial Commission of Health and Family Planning, a Jiangsu Higher Education Institution Innovative Research Team grant, the National Natural Science Foundation of China, and a Scientific and Technological Innovation Team grant from Jiangsu Medical College. The authors reported no conflicts of interest. Ethical approval was granted by the Ethics Committee of the Second Affiliated Hospital of Zhejiang University School of Medicine, and all participants gave written informed consent.
Publication Details
The study, titled ‘Dose-Response Relationship Between Workplace Psychological Stress Accumulation Index and Erectile Function in Young Men,’ was authored by Wenjie Huang, Yiyu Qin, Yuping Chen, Guozhe Zhang, Bodong Lv, Zhiyue Wu, and Yang Zhou, affiliated with the Second Affiliated Hospital of Zhejiang University School of Medicine and Jiangsu Medical College. It was published in the International Journal of Clinical Practice (2026), DOI: 10.1155/ijcp/7492091.







